
Journal of Medicinal Chemistry p. 658 - 663 (1982)
Update date:2022-08-16
Topics: Synthesis In vitro Bioassay in vivo Purification Anthelmintic Acyl derivatives Avermectin
Mrozik, Helmut
Eskola, Philip
Fisher, Michael H.
Egerton, John R.
Cifelli, Sam
Ostlind, Dan A.
Avermectins A2a, B1a, and B2a (1, 2, and 3) were acetylated to give 4''- and 23-acetates 4 and 5 and 4'',23-diacetate 6 from 1, the 4''- and 5-acetates 7 and 8 and 4'',5-diacetate 9 from 2, and triacetate 10 from 3.Structu
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