SYNTHESIS OF OPTICALLY PURE ENKEPHALIN ANALOG, ENKEPHALIN, USING CHIRAL β-LACTAMS AS SYNTHETIC INTERMEDIATES

DOI: 10.1246/cl.1982.445

Source and publish data:

Chemistry Letters p. 445 - 448 (1982)

Update date:2022-08-04

Topics:

Authors:

Hatanaka, Naoto

Abe, Rumiko

Ojima, Iwao

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1246/cl.1982.445

Optically pure pentapeptide, L-Tyr-D-Ala-Gly-L-Phe-L-Leu-ol (1) wich is an analog of opioid hormone. enkephalin, was succesfully synthesized by using β-lactam building blocks as synthons of peptide units.

Full text of DOI:10.1246/cl.1982.445

Products guided by the article

Product name:(R)-2-[(2R,3S)-3-Azido-2-(4-benzyloxy-phenyl)-4-oxo-azetidin-1-yl]-propionic acid tert-butyl ester

Cas No:82101-52-8

R&D Labs maybe for 82101-52-8

SYN Pharma Co., Ltd

Contact:86-21 60347964

Address:No.1304, West Meilong Road, Minhang District, Shanghai, China
Ji'nan Orgachem Pharmaceutical Co.,Ltd

Contact:+86-531-82687810

Address:Jinan
Shuanghe Bio-Technology Limited(expird)

Contact:+86-571-61710758,18968016640

Address:Jinqiao north road 916# Fuyang
Chengdu CSH Pharmaceutical Co.,ltd

Contact:+86-(28)-85321971

Address:Block B,New Hope Int. Tian Fu New District, Chengdu, Sichuan, China
Borun Chemical Co.,Ltd.

Contact:+86-574- 87178138; 87297407

Address:No. 809, Liudingxingzuo, cangsong road, Ningbo, China

Relevant to this article

Synthesis and antibacterial activities of enamine derivatives of dehydroacetic acid

Doi:10.1007/s00044-017-2110-8
(2018)
Doi:10.1007/BF00909956
(1962)
Synthesis, binding affinities and metabolic stability of dimeric dermorphin analogs modified with β³-homo-amino acids

Doi:10.1002/psc.2869
(2016)
Synthesis and anticancer evaluation of certain indolo[2,3-b]quinoline derivatives

Doi:10.1016/j.bmc.2004.09.025
(2004)
Design, synthesis, and testing of potential antisickling agents. I. Halogenated benzyloxy and phenoxy acids

Doi:10.1021/jm00351a002
(1982)
AN ELEGANT SYNTHESIS OF SOME NATURALLY OCCURRING LINEAR ACETYLCHROMENES: EUPATORIOCHROMENE, METHYLEUPATORIOCHROMENE (ENCECALIN); EVODIONOL AND METHYLEVODIONOL

Doi:10.1016/0040-4020(82)80200-7
(1982)

Article Doi