Journal of Organic Chemistry p. 3306 - 3310 (1982)
Update date:2022-08-03
Topics:
Marx, John N.
Minaskanian, Gevork
The first regiospecific total synthesis of the anticancer compound sarkomycin (1) is described.The starting material is 2-(carbomethoxycyclopent-2-enone (4), a useful precursor for cyclopentanoid natural products.The cyano derivative 5, the amide derivative 6, and the keto lactone 9 were also synthetized.The latter may be considered as a "cyclized" form of sarkomycin and was shown to open slowly to the natural product upon treament with dilute acid.
View MoreXI'AN CHUKANG BIOTECHNOLOGY CO.,LTD
Contact:29-63685658 63685359
Address:Room 3-1202,Building 1,Oriental oasis,East of Xianning Road,Xi'an,Shaanxi 710043 P.R.China
Shenzhen Sungening Medicine Co., Ltd
Contact:+86-871-65110906
Address:Room702, Building 2, 365 Dianchi Road, Kunming, Yunnan Province, P.R. China
shandong lukang animal & plant drug trading co.,ltd.
Contact:15853765968
Address:floor 9, lukang ,jingying building,#173,taibai building west road,jining city,shandong,china
Baoding City Light Industry And Textiles Imp.& Exp. Corp. Chemical Department.
Contact:86-312-3262436
Address:NO.658 CHAOYANG SOUTH STREET,BAODING CITY HEBEI CHINA
CGeneTech (Suzhou, China) Co., Ltd.
Contact:+86-512-62956962
Address:Room 101，Bld C11,218 Xinghu Rd.,Suzhou industrial Park
Doi:10.1007/s12039-017-1223-4
(2017)Doi:10.1021/ja00384a071
(1982)Doi:10.1021/ja00380a040
(1982)Doi:10.1021/ol048161l
(2004)Doi:10.1021/jo00176a002
(1984)Doi:10.1016/S0040-4039(00)87103-8
(1982)
