
Journal of the American Chemical Society p. 4604 - 4610 (1982)
Update date:2022-08-03
Topics:
Boeckman, Robert K.
Sum, F.-W.
An 11-step total synthesis of (+/-)-aklavinone from 1,3-cyclohexadione is reported.The key steps include a Diels-Alder condensation of 3 and 4 and the stereoselective aldol condensation of 21 to 22.The overall yield is ca. 13percent.
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Doi:10.1021/ol047768z
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(1982)