METAL IONS AS SELECTIVE TRIGGERS FOR REMOVING OLIGODEOXYNUCLEOTIDE PHOSPHOTRIESTER PROTECTING GROUPS

DOI: 10.1016/S0040-4039(00)86807-0

Source and publish data:

Tetrahedron Letters p. 275 - 278 (1982)

Update date:2022-08-04

Topics:

Authors:

Stabinsky, Y.

Sakata, R. T.

Caruthers, M. H.

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Article abstract of DOI:10.1016/S0040-4039(00)86807-0

The o-bromophenyl group was successfully tested as a phosphotriester protecting group for internucleotide bonds.This protecting group can be readily and selectively removed using various transition metal salts in aqueous pyridine.

Full text of DOI:10.1016/S0040-4039(00)86807-0

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