Journal of Organic Chemistry p. 4265 - 4268 (1982)
Update date:2022-08-04
Topics:
Mubarak, Azeez
Fraser-Reid, Bert
Routes to 3-C-cyano-3-deoxy-D-galactopyranose derivatives have been developed from methyl 3,4-anhydro-α-D-galactopyranoside and 1,6:3,4-dianhydro-β-D-galactopyranose.Upon treatment with diethylaluminum cyanide, both precursors give products of trans-diaxial opening although some diequatorial opening also occurs with the former.The axial C-cyano groups in both cases are readily epimerized by dilute sodium methoxide, giving 3-C-cyano-3-deoxy-D-galacto products.In neither case is there any evidence of β elimination or of skeletal rearrangements.
View MoreContact:86-0311-88310000
Address:Room 1109 Sunshine Plaza,No.46 Tang Gudun Road,Jianghan District Wuhan Hubei
website:http://www.josunpharma.com
Contact:+86-311-80715268 80766839
Address:No.39, Zhaiying Street, Shijaizhuang,Hebei,China
Shanghai ZaiQi Bio-Tech Co., Ltd.,
Contact:+86-21-5482 4098
Address:Bldg. No.7, No.201 MinYi Rd,Songjiang CaoHeJing High-Tech Park Shanghai 201516 P,R,China
Contact:(1) 206-3550089
Address:5115 NE 8TH PL, Renton, WA 98059 USA
AllyChem Co., Ltd., Dalian, China(BBChem)
Contact:+86-411-62313318/62313328
Address:No.5 of Jinbin Road, Jinzhou New District, Dalian City, Liaoning Province, P.R.China
Doi:10.1021/jo01318a017
(1979)Doi:10.1080/10426500108040598
(2001)Doi:10.1016/j.poly.2003.10.013
(2004)Doi:10.1016/S0022-328X(00)84978-5
(1973)Doi:10.1016/S0008-6215(00)84219-6
(1978)Doi:10.1080/00397919708006059
(1997)