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Furthermore, the possibility of a radical process was ruled out after
performing the reactions in the presence of well-known radical
scavengers TEMPO and 1,1-diphenylethylene (DPE). In both the
reactions conducted using a-fluoro-a-nitroacetamide 1a, the desired
product 3a was obtained in 80% and 74% respectively.
In conclusion, the use of diaryliodonium salts as arylating
agents has enabled the development of a convenient metal-free
protocol for the a-arylation of synthetically valuable a-fluoro-a-
nitroacetamides for the creation of a quaternary benzylic fluoro-
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wide range of electronically varied arenes, thereby representing
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M. K. Z. and E. G. are grateful to CSIR and UGC-New Delhi
for the awards of Research Fellowships. We thank Dr Tejender
S. Thakur, MSB Division, CSIR-CDRI, for supervising the X-ray data
collection and structure determination. We thank the SAIF Division
for analytical support. CDRI Communication No. 10006.
Conflicts of interest
There are no conflicts to declare.
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156 | Chem. Commun., 2020, 56, 153--156
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