Tetrahedron p. 1527 - 1530 (1982)
Update date:2022-08-04
Topics:
Abdelhamid, Abdou O.
Hassaneen, Hamdi M.
Abbas, Ikhlass M.
Shawali, Ahmad S.
Diazotized anthranilic acid and its methyl ester react with substituted α-thiocyanatoacetoacetanilides 3a-c to give in both cases the corresponding thiadiazolo<2,3-b> quinazolines 6a-c, respectively.A mechanism is proposed and it is substantiated by synthesis of 6a from N-(2-carboxyphenyl)-C-phenylcarbamoyl hydrazidoyl chloride 8a or its N-(2-methoxycarbonylcarbonylphenyl) analogue 8d.
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(2011)Doi:10.1021/jm100751q
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