Journal of the American Chemical Society p. 7181 - 7190 (1982)
Update date:2022-08-03
Topics: Stereochemistry Scope Experimental terms
Ziegler, Frederick E.
Piwinski, John J.
The complete details of the seminal study on the tandem Cope-Claisen rearrangement are presented.The reaction uses an initial Cope rearrangement to trigger an irreversible Claisen rearrangement.In several cases, the Claisen step drives an unfavorable Cope
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