Synthesis of 1-(Aminomethyl)-1,2,3,4-tetrahydroisoquinolines and Their Actions at Adrenoceptors in Vivo and in Vitro

DOI: 10.1021/jm00358a010

Source and publish data:

Journal of Medicinal Chemistry p. 507 - 515 (1983)

Update date:2022-08-05

Topics:

Authors:

Beaumont, David

Waigh, Roger D.

Sunbhanich, Methi

Nott, Michael W.

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Article abstract of DOI:10.1021/jm00358a010

An improved synthesis of 1-(aminomethyl)-1,2,3,4-tetrahydroisoquinolines has been developed by using aluminum hydride reduction of 1-cyano-1,2,3,4-tetrahydroisoquinolines.Three 1-(aminomethyl)-6,7-dihydroxytetrahydroisnolines

Full text of DOI:10.1021/jm00358a010

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Product name:2-benzyl-1-cyano-6,7-bis(benzyloxy)-1,2,3,4-tetrahydroisoquinoline

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