PREPARATION AND STEREOCHEMISTRY OF 1,4,8,11-TETRAAZAPERHYDROPYRENE DERIVATIVES FROM N,N'-BIS(3-AMINOPROPYL)ETHYLENEDIAMINE

Article abstract of DOI:10.3987/COM-95-7038

The reaction of N,N'-bis(3-aminopropyl)ethylenediamine (1) with glyoxal (2) in the presence of benzotriazole (3) afforded dibenzotriazoyltetraazaperhydropyrene (4), which was converted to polyazapolycycles (6), (13), (15), (16), and (19).The stereochemistry is discussed.