Chiral Cyclopentanoid Synthetic Intermediates via Asymmetric Microbial Reduction of Prochiral 2,2-Disubstituted Cyclopentanediones

DOI: 10.1021/jo00135a039

Source and publish data:

Journal of Organic Chemistry p. 2820 - 2821 (1982)

Update date:2022-08-05

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Authors:

Brooks, Dee W.

Grothaus, Paul G.

Irwin, William L.

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Article abstract of DOI:10.1021/jo00135a039

A prochiral distinction by microbial reduction of 2-propyl- (1), 2-allyl- (4), and 2-propynyl-2-methyl-1,3-cyclopentanedione (7) with bakers' yeast provides efficient access to several chiral cyclopentanoid synthetic intermediates.A short enantioselective

Full text of DOI:10.1021/jo00135a039

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