Angiotensin-converting enzyme inhibitors: Synthesis and biological activity of acyl tripeptide analogues of enalapril

DOI: 10.1021/jm00382a008

Source and publish data:

Journal of Medicinal Chemistry p. 434 - 442 (1985)

Update date:2022-08-05

Topics: Synthesis High-performance liquid chromatography (HPLC) Analogues Biological Activity Synthesis reaction Angiotensin-converting enzyme inhibitors

Authors:

Greenlee

Allibone

Perlow Perlow

Patchett

Ulm Ulm

Vassil Vassil

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jm00382a008

The synthesis and biological activity of a series of inhibitors of angiotensin-converting enzyme (EC 3.4.15.1) are described. Incorporation of the substituted N-carboxymethyl dipeptide design of enalapril (MK-421) into acyl tripeptides and larger peptides

Full text of DOI:10.1021/jm00382a008

Products guided by the article

Product name:N-(2-benzamideo-1-carbomethoxyethyl)-Ala-Pro

Cas No:84759-84-2

R&D Labs maybe for 84759-84-2

Evershine Chemical CO Ltd

Contact:+86-571-87010026

Address:202, Zhenhua Road,
Deer Chemicals Co., Ltd.

Contact:+86-13666670345

Address:Agricultural Development Zone, Haining, Jiaxing, Zhejiang
Jining tiansheng chemical co.,ltd.

Contact:+86-537-5158722

Address:ROOM 1011, BLOCK B, CUIDU INTERNATIOAL BUSINESS CENTER, JINING CITY, CHINA
ZHEJIANG NHU COMPANY LTD.

Contact:86-575-86132822，86-575-86085355

Address:No.418 Dadao West Road,Qixing Street,Xinchang, Zhejiang Province, China.
LIAOYANG WANRONG CHEMICALS COMPANY LIMITED

Contact:86-419-2390789

Address:XINLI VILLAGE , DONG NINGWEI COUNTY,TAIZIHE DISTRICT, LIAOYANG , LIAONING

Relevant to this article

Conformation analyses, dynamic behavior, and amide bond distortions of medium-sized heterocycles. 2. Partially and fully reduced 1-benzazocines, benzazonines, and benzazecines

Doi:10.1021/jo048117j
(2005)
Studies on the constituents of Osmanthus species. X. Structures of phenolic glucosides from the leaves of Osmanthus asiaticus NAKAI

Doi:10.1248/cpb.40.325
(1992)
Synthesis and evaluation of CCR5 antagonists containing modified 4-piperidinyl-2-phenyl-1-(phenylsulfonylamino)-butane

Doi:10.1016/j.bmcl.2004.12.044
(2005)
Observation of a new dimeric amino acid derivative in the reaction of methyl N-BOC-(S)-(3-fluorophenyl)alanate with DIBAL-H and lithio ethyl propiolate

Doi:10.1016/S0957-4166(01)00054-4
(2001)
Synthesis and in vitro antitumor activity of some amino-deoxy 7-hexofuranosylpyrrolo[2,3-d] pyrimidines

Doi:10.1016/S0008-6215(98)00098-6
(1998)
A highly efficient three-component coupling of aldehyde, terminal alkyne, and amine via C-H activation catalyzed by reusable immobilized copper in organic-inorganic hybrid materials under solvent-free reaction conditions

Doi:10.1016/j.tet.2007.04.032
(2007)

Article Doi