Journal of Medicinal Chemistry p. 434 - 442 (1985)
Update date:2022-08-05
Topics: Synthesis High-performance liquid chromatography (HPLC) Analogues Biological Activity Synthesis reaction Angiotensin-converting enzyme inhibitors
Greenlee
Allibone
Perlow
Patchett
Ulm
Vassil
The synthesis and biological activity of a series of inhibitors of angiotensin-converting enzyme (EC 3.4.15.1) are described. Incorporation of the substituted N-carboxymethyl dipeptide design of enalapril (MK-421) into acyl tripeptides and larger peptides
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