Antihypertensive β-adrenergic blocking agents: N-aralkyl analogues of 2-[3-(tert-butylamino)-2-hydroxypropoxy]-3-cyanopyridine

DOI: 10.1021/jm00359a006

Source and publish data:

Journal of Medicinal Chemistry p. 649 - 657 (1983)

Update date:2022-08-05

Topics:

Authors:

McClure McClure

Baldwin Baldwin

Randall Randall

Lyon Lyon

Mensler Mensler

Lundell Lundell

Raab Raab

Gross Gross

Risley Risley

Sweet Sweet

Williams

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Article abstract of DOI:10.1021/jm00359a006

An interest in dual-acting antihypertensive agents, specifically those related to (S)-2-[3-(tert-butylamino)-2-hydroxypropoxy]-3-cyanopyridine (1), led us to probe the contribution of the side-chain amino substituent in this series. The ability of 1 and i

Full text of DOI:10.1021/jm00359a006

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