Total synthesis of caprazol, a core structure of the caprazamycin antituberculosis antibiotics

Article abstract of DOI:10.1002/anie.200462439

TB and anti-TB: Two key steps in the synthesis of caprazol (1), a core structure of the antituberculosis antibiotics, are the introduction of an aminoribose moiety by β-selective ribosylation without the use of neighboring-group participation and the construction of the diazepanone moiety. (Chemical Equation Presented)