Bioorganic and Medicinal Chemistry Letters p. 5182 - 5185 (2009)
Update date:2022-09-26
Topics:
Patel, Hitesh K.
Grotzfeld, Robert M.
Lai, Andiliy G.
Mehta, Shamal A.
Milanov, Zdravko V.
Chao, Qi
Sprankle, Kelly G.
Carter, Todd A.
Velasco, Anne Marie
Fabian, Miles A.
James, Joyce
Treiber, Daniel K.
Lockhart, David J.
Zarrinkar, Patrick P.
Bhagwat, Shripad S.
A series of diaryl ureas with an amide substitution at the 4-position was prepared and found to be potent and selective FLT3 inhibitors with good oral bioavailability and efficacy in a tumor xenograft model.
View Morewebsite:http://www.eastarchem.com/
Contact:1-800-898-2436
Address:1215 K Street, STE 1700
Synchem Pharma Co.,Ltd(expird)
Contact:+0086-21-61984905-1
Address:Building 60,Zimian Park, LongYang industrial Area, 1515Nong，Yuandong Road Fengxian District, Shanghai ,China
Beijing Wisdom Chemicals Co., Ltd.
Contact:+86-10-52350335
Address:F2, BLDG 19, Liando Valley U, Majuqiao, Tongzhou District, Beijing, China
Weifang Ocean Trading Co., Ltd.
Contact:+86-536-2081155
Address:Room2606, Yuqing Building, 518#, Yuquan Road, High-tech Development Zone, Weifang City, Shandong Province, China
Shanghai Kangxin Chemical Co., Ltd
Contact:+86 21 60717227
Address:118,Ganbai Village,Waigang Town,Jiading District,Shanghai
Doi:10.1016/j.bmcl.2005.03.015
(2005)Doi:10.1021/ol050558h
(2005)Doi:10.1016/j.tetlet.2007.09.037
(2007)Doi:10.1021/jo50008a018
(1952)Doi:10.1016/j.jorganchem.2009.08.014
(2009)Doi:10.1021/jo01233a006
(1936)
