Phase-Transfer Catalyzed Synthesis of Amides and Esters of Carboxylic Acids

DOI: 10.1055/s-1989-27380

Source and publish data:

Synthesis p. 745 - 747 (1989)

Update date:2022-08-05

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Authors:

Jaszay, Zsuzsa M.

Petnehazy, Imre

Toeke, Laszlo

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Article abstract of DOI:10.1055/s-1989-27380

A convenient one-pot procedure is reported for the preparation of carboxamides and carboxylic acid esters from carboxylic acids and amines or alcohols, respectively.The carboxylic acids are activated by sulfonyl chlorides under solid-liquid phase-transfer conditions using solid potassium carbonate as base and a lipophilic quaternary ammonium salt as catalyst.

Full text of DOI:10.1055/s-1989-27380

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