FLUOROMETHYL PHENYL SULFOXIDE: HIGHLY CONVENIENT SYNTHESES OF VINYL FLUORIDES AND FLUOROMETHYLKETONES

Article abstract of DOI:10.1016/S0040-4039(00)81509-9

Alkylation of lithio fluoromethyl phenyl sulfoxide 2 gave the alkylated products in high yields.Pyrolysis of the products led to vinyl fluorides in excellent yields.The reaction of 2 with carbonyl compounds led to the corresponding β-hydroxy-α-fluoromethyl phenyl sulfoxides.Pyrolysis of some of the sulfoxides gave fluoromethylketones in moderate yields.