
Chemical and Pharmaceutical Bulletin p. 45 - 51 (1983)
Update date:2022-08-03
Topics:
Lancelot
Gazengel
Rault
Robba
The synthesis of the new heterocycles pyrrolo[1',2':1,2]pyrazino[6,5-b]carbazoles was achieved by the intramolecular cyclisation of 2-(1-pyrrolyl)carbazole derivatives. These latter compounds were obtained by the Clauson-Kaas reaction starting from the corresponding 2-aminocarbazoles, obtained by reduction of 2-nitrocarbazoles. A study of this reduction has shown that the introduction of acetyl grouping in position 9 makes this reaction easier and gives better results than previous methods. 1H-NMR spectra are studied.
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Doi:10.1016/S0040-4039(00)86394-7
(1983)Doi:10.1248/cpb.44.720
(1996)Doi:10.1021/ja051694k
(2005)Doi:10.1021/ja0547230
(2005)Doi:10.1016/j.poly.2004.04.008
(2004)Doi:10.1016/S0960-894X(02)00646-7
(2002)