Journal of Medicinal Chemistry p. 7374 - 7388 (2005)
Update date:2022-08-05
Topics:
Zheng, Guo Zhu
Bhatia, Pramila
Daanen, Jerome
Kolasa, Teodozyj
Patel, Meena
Latshaw, Steven
El Kouhen, Odile F.
Chang, Renjie
Uchic, Marie E.
Miller, Loan
Nakane, Masaki
Lehto, Sonya G.
Honore, Marie P.
Moreland, Robert B.
Brioni, Jorge D.
Stewart, Andrew O.
SAR (structure-activity relationship) studies of triazafluorenone derivatives as potent mGluR1 antagonists are described. The triazafluorenone derivatives are non-amino acid derivatives and noncompetitive mGluR1 antagonists that bind at a putative alloste
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(1983)