SYNTHESIS OF β-D-GLUCOPYRANOSYLVALIDAMINE: 2-O-β-D-GLUCOPYRANOSYL-1L-(1,3,4/2,6)-4-AMINO-6-HYDROXYMETHYL-1,2,3-CYCLOHEXANETRIOL

Article abstract of DOI:10.1246/cl.1980.135

β-D-Glucopyranosylvalidamine (1a), the structure of which was assigned to the degradation product of validamycin A, was synthesized by condensation of a protected validamine (8) with acetobromoglucose, followed by deblocking.Unexpectedly, 1a was found not to be identical with an authentic sample derived from the antibiotic