Journal of Medicinal Chemistry p. 87 - 91 (1984)
Update date:2022-08-04
Topics:
Scovill, John P.
Klayman, Daniel L.
Lambros, Chris
Childs, George E.
Notsch, John D.
In view of the antimalarial activity in mice 2-acetylpyridine thiosemicarbazones, a series of analogues 1-oxides was prepared for evaluation.Their synthesis was achieved by the reaction of 2-acetylpyridine 1-oxide with methylhydrazinecarbodithioate to giv
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