Chemistry of Naturally Occurring Polyamines. 7. Selective Functionalization of Hydroxyputrescine

Article abstract of DOI:10.1021/jo00173a049

As part of a program to synthesize biologically interesting polyamines and their conjugates, we report studies on the structure and reactivity of hydroxyputrescine-aldehyde adducts which permit regioselective functionalization of this rather rare naturall