Journal of the Chemical Society. Perkin transactions II p. 1369 - 1372 (1983)
Update date:2022-07-29
Topics:
Suttle, Nicola A.
Williams, Andrew
NN'-Di-isopropyl-O-arylisoureas are demonstrated to rearrange intramolecularly to the corresponding NN'-di-isopropyl-N'-arylurea in alkaline solution.The large negative Broensted-type βL value (-2.3) for the reaction measured against the pK of the corresponding phenol and a modest entropy of activation are consistent with a 1,3-aryl migration.The high efficiency of the migration compared with that of the Chapman rearrangement of O-aryl imidoethers is attributed to the greater internal nucleophilicity of the imino nitrogen, which in the present case bears a negative charge.
View MoreChengdu King-tiger Pharm-chem. Tech. Co., Ltd
Contact:028-85317716
Address:Tianfu Life Science Park, No. 88 South Keyuan Road, Gaoxin District, Chengdu City, Sichuan Province, PRC.
website:http://www.fwdchem.com
Contact:86-21-54450828
Address:Room 802,Lotus Tower ,159 Tianzhou Road,Xuhui District,Shanghai
Weihao Chemtech (ChangZhou) Co., Ltd.(expird)
Contact:051989185693
Address:NO 217 huangshan Rd ,Changzhou
Jiaxing Anrui Material Technology Co., Ltd.
Contact:86-573-82651652 13305832579
Address:Room 407, Technology Building, 1369 Chennan Road, Jiaxing City, Zhejiang, China
Tianjin Te-An Chemtech Co., Ltd.(expird)
Contact:+86-22-65378638
Address:A5-8, No.80 Haiyun Street, TEDA
Doi:10.1080/00397910500408225
(2006)Doi:10.1016/j.tet.2007.09.031
(2007)Doi:10.1007/s11172-007-0021-4
(2007)Doi:10.1016/0008-6215(83)84049-X
(1983)Doi:10.1016/S0040-4039(00)88246-5
(1983)Doi:10.1007/BF00516449
(1983)
