
Tetrahedron Letters p. 3509 - 3512 (1983)
Update date:2022-08-05
Topics:
Kobayashi, Kazuhiro
Hiyama, Tamejiro
Highly selective cross-Thorpe reaction is achieved between an α-lithioalkanenitriles and a protected cyanohydrin to give 4-alkoxy-4-amino-2-alkenenitrile, which, in turn, is converted by deprotection and acetylation followed by hydrogenolysis to 3-amino-2
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