Tetrahedron Letters p. 3311 - 3314 (1983)
Update date:2022-08-05
Topics:
Seebach, Dieter
Aebi, Johannes, D.
The (S,S)- and the (S,R)-oxazolines 4, both readily available from L-threonine, are deprotonated with lithium diisopropylamide (LDA, -> 5) and alkylated diastereoselectively (>95 percent ds) to yield the 4,4-disubstituted oxazolines 7.The product of methy
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