Molecular Pharmaceutics p. 532 - 537 (2013)
Update date:2022-08-03
Topics:
Huttunen, Kristiina M.
Tani, Niina
Juvonen, Risto O.
Raunio, Hannu
Rautio, Jarkko
Four novel cyclic phosphates of the anti-inflammatory agent 5-aminosalicylic acid (5-ASA) were designed and synthesized as cytochrome P450 (CYP)-activated prodrugs. These prodrugs can be used for targeting into gut wall, since these types of cyclic phosph
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