Journal of Medicinal Chemistry p. 536 - 539 (1984)
Update date:2022-08-03
Topics:
Awaya, Hiroyoshi
May, Everette L.
Aceto, Mario D.
Merz, Herbert
Rogers, Michael E.
Harris, Louis S.
2,9α-Dimethyl-5-(m-hydroxyphenyl)morphan (3a) has been synthesized from 5-(m-methoxyphenyl)-2-methyl-9-oxomorphan (4) and resolved into its enantiomers (+)-3a and (-)-3a.The assigned α-orientation of the 9-methyl group was derived from studies of induced
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