Tetrahedron Letters p. 5393 - 5396 (1994)
Update date:2022-08-04
Topics:
Hanessian, Stephen
Meng, Quingchan
Olivier, Eric
When treated with a reagent prepared from equimolar quantities of methyllithium and copper iodide, 7,21-di-O-TMS bafilomycin A2 3 undergoes ring expansion to give the 18-membered lactone homolog 5 in nearly quantitative yield.Acid hydrolysis gives iso-bafilomycin A1.Ring contraction to the original 16-membered lactone takes place in the presence of fluoride ion.A mechanistic rationale and X-ray crystallographic evidence are presented.
View MoreHangzhou LINGEBA Technology Co., Ltd.
Contact:+0086-571-87389059
Address:Office 1-913,NewYouth Plaza, GongShu Area, HangZhou,ZheJiang,P.R.China
Shandong Shouguang Songchuan Industrial Additives Co.,Ltd
Contact:+86-536-8566856
Address:Shouguang,Shandong,China
Contact:+86-22-83718541
Address:32th Floor, Rongqiao Center Intersection of Changjiang Road and Nankai Six Road Nankai District Tianjin 300102, China
Shenzhen Hongyuan Import & Export Co., Ltd.
Contact:0755-26407171
Address:Shenzhen Hongyuan Chemical New Materials Technology Co., Ltd.
Contact:410-273-7300; 800-221-3953
Address:4609 Richlynn Dr., PO Box 369, Belcamp, MD, 21017-0369, USA
Doi:10.1021/om0602198
(2006)Doi:10.1002/anie.202103806
(2021)Doi:10.1016/S0040-4020(01)91556-X
(1983)Doi:10.1016/j.tet.2005.12.065
(2006)Doi:10.1248/cpb.31.3728
(1983)Doi:10.1080/15257779408009479
(1994)
