Uracil derivatives. IV. Growth-inhibitory activity against L-1210 cells of orotic acid derivatives and synthesis of 1-(β-D-ribofuranosyl)furo[3,4-d]pyrimidine-2,4,7(1H,3H,5H)-trione

DOI: 10.1248/cpb.31.3074

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Chemical and Pharmaceutical Bulletin p. 3074 - 3083 (1983)

Update date:2022-08-05

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Authors:

Okada Okada

Nakano Nakano

Miyake Miyake

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Article abstract of DOI:10.1248/cpb.31.3074

5-(Substituted thiomethyl)-6-carbamoyluracils (IIIb-h) and 5-(substituted thiomethyl)-uracils (Va-h) were prepared and their ability to inhibit the growth of L-1210 cells in vitro was examined. The reaction of silylated furo[3,4-d]pyrimidine-2,4,7(1H,3H,5

Full text of DOI:10.1248/cpb.31.3074

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