Synthesis of the Two Enantiomers of a Tetrahydro-β-carboline from L-(-)-Tryptophan

DOI: 10.1039/c39830001147

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Journal of the Chemical Society. Chemical communications p. 1147 - 1149 (1983)

Update date:2022-08-05

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Authors:

Massiot, Georges

Mulamba, Tshilundu

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Article abstract of DOI:10.1039/c39830001147

Pictet-Spengler condensations of methyl 4-formyl-2,2-bis(phenylthio)butyrate with tryptophanamide and N^b-benzyltryptophanamide are stereospecific; dehydration of the adducts <(CF3CO)2O> followed by cyanide elimination (NaBH4) yields tetrahydro-

Full text of DOI:10.1039/c39830001147

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