Aryldithioethyloxycarbonyl (Ardec): A new family of amine protecting groups removable under Mild reducing conditions and their applications to peptide synthesis

DOI: 10.1002/chem.200501538

Source and publish data:

Chemistry - A European Journal p. 3655 - 3671 (2006)

Update date:2022-08-04

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Authors:

Lapeyre, Milaine

Leprince, Jerome

Massonneau, Marc

Oulyadi, Hassan

Renard, Pierre-Yves

Romieu, Anthony

Turcatti, Gerardo

Vaudry, Hubert

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Article abstract of DOI:10.1002/chem.200501538

The development of phenyl-dithioethyloxycarbonyl (Phdec) and 2-pyridyldithioethyloxycarbonyl (Pydec) protecting groups, which are thiollabile urethanes, is described. These new disulfide-based protecting groups were introduced onto the ε-amino group of L-

Full text of DOI:10.1002/chem.200501538

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