Inter- and intramolecular addition of ester anions to nicotinium salts. A facile approach to nauclefine and ellipticine derivatives

DOI: 10.1016/S0040-4020(01)88606-3

Source and publish data:

Tetrahedron p. 3673 - 3681 (1983)

Update date:2022-08-05

Topics:

Authors:

Wanner Wanner

Koomen Koomen

Pandit Pandit

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Article abstract of DOI:10.1016/S0040-4020(01)88606-3

Reaction of ester anions with 1-(2'-indolyl-ethyl)nicotinium chloride and 1-(1'-methyl-2'-indolylethyl)-nicotinium chloride leads to 2,7-naphthyridine-1,3-diones. Acid catalyzed cyclization of the latter yield pentacyclic napthyridocarboline derivatives.

Full text of DOI:10.1016/S0040-4020(01)88606-3

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