HIGHLY EFFICIENT ASYMMETRIC SYNTHESIS OF (S)-2,2-DIMETHYL-1,3-DIOXOLANE-4-METHANOL FROM GLYCEROL

Article abstract of DOI:10.1246/cl.1984.401

(S)--2,2-Dimethyl-1,3-dioxolane-4-methanol was prepared from glycerol in high yield with high optical purity by simple procedure.The procedure involves acylation of cyclic tin(IV) alkoxide with an optical active acid chloride in the crucial step.