Bioorganic and Medicinal Chemistry Letters p. 5444 - 5448 (2009)
Update date:2022-08-05
Topics: Synthesis Inhibitors Lead compound Mass spectrometry (MS) IC50 High-performance liquid chromatography (HPLC) Enzyme inhibition Structure-Activity Relationship (SAR) Pharmacokinetics Substrate Bioavailability In vitro assay In vivo study Metabolite Competitive inhibition Non-competitive inhibition Ki (Inhibition constant) Half-life (t?)
Flentge, Charles A.
Randolph, John T.
Huang, Peggy P.
Klein, Larry L.
Marsh, Kennan C.
Harlan, John E.
Kempf, Dale J.
The HIV protease inhibitor ritonavir (RTV) is also a potent inhibitor of the metabolizing enzyme cytochrome P450 3A (CYP3A) and is clinically useful in HIV therapy in its ability to enhance human plasma levels of other HIV protease inhibitors (PIs). A nov
View MoreWUHU HUAHAI BIOLOGY ENGINEERING CO LTD
Contact:+86-553-3836920
Address:7/F NO.82 LAODONG ROAD WUHU CHINA
Pengchen New Material Technology Co., Ltd.
Contact:+86-512-63680537
Address:99.6 km of national road 318, Meiyan Community,Pingwang Town, Wujiang District, Suzhou 215225
Zhejiang Chemline International Co., Ltd.
Contact:+86-571-88062298
Address:Hengdian Industry Area, Dongyang, Zhejiang, China
website:http://www.jairadhesales.com
Contact:0091-79-26431096
Address:309 Harikrupa Tower,Nr old Sharda Mandir Char Rasta,Ellisbridge
Shao Xing Empire Import&Export CO.,ltd
Contact:86-575-82127757
Address:11#, Weiwu Road, Shangyu Industrial Park, Hangzhou Bay, Hangzhou, Zhejiang Province, China
Doi:10.1021/jo00191a009
(1984)Doi:10.1016/j.jorganchem.2012.05.033
(2012)Doi:10.1055/s-2006-941584
(2006)Doi:10.1016/0040-4020(84)85065-6
(1984)Doi:10.1007/BF00515642
(1984)Doi:10.1016/S0040-4039(00)99926-X
(1984)
