Synthesis and in Vitro Biological Evaluation of N--3-(hydroxynitrosamino)-L-alanine (L-Alanosine AICO Ribonucleoside)

DOI: 10.1021/jm00376a012

Source and publish data:

Journal of Medicinal Chemistry p. 1295 - 1299 (1984)

Update date:2022-08-05

Topics:

Authors:

Strazzolini, Paolo

Malabarba, Adriano

Ferrari, Pietro

Grandi, Maria

Cavalleri, Bruno

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Article abstract of DOI:10.1021/jm00376a012

L-Alanosine <3-(hydroxynitrosoamino)-L-alanine> is an antitumor antibiotic that at the present is undergoing phase II clinical trials.Its mode of action as well as its metabolism has been extensively studied, and the metabolite N-<(5-amino-1-β-D-ribofuran

Full text of DOI:10.1021/jm00376a012

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