Bioorganic and Medicinal Chemistry Letters p. 2015 - 2020 (1997)
Update date:2022-08-03
Topics:
Cebula, Regina E.
Blanchard, Jill L.
Boisclair, Michael D.
Pal, Kollol
Bockovich, Nicholas J.
Analogs of sulfircin (1) were synthesized and tested for inhibitory activity against a panel of phosphatases. We attempted to optimize the potency and selectivity of sulfircin for Cdc25A by modifying three structural areas of the molecule. An anionic grou
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