Acetylenic amides. 1. Synthesis of N-substituted-2-propynamides

Article abstract of DOI:10.1080/00397919308009860

The efficient synthesis of N-substituted-2-propynamides was accomplished by three methods; the reaction of amines with either the N-hydroxysuccinimide ester or mixed anhydride of propiolic acid, or by the interaction of lithiotrimethylsilylacetylene with

Full text of DOI:10.1080/00397919308009860

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Synthetic Communications: An
International Journal for Rapid
Communication of Synthetic
Organic Chemistry
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Acetylenic Amides. I.
Synthesis of N-Substituted-2-
propynamides
Gary M. Coppola a & Robert E. Damon a
a Sandoz Research Institute, Chemistry Research
Department Sandoz, Inc. , Route 10, East Hanover,
New Jersey, 07936
Published online: 16 Feb 2007.
To cite this article: Gary M. Coppola & Robert E. Damon (1993) Acetylenic Amides.
I. Synthesis of N-Substituted-2-propynamides, Synthetic Communications: An
International Journal for Rapid Communication of Synthetic Organic Chemistry, 23:14,
2003-2010, DOI: 10.1080/00397919308009860
To link to this article: http://dx.doi.org/10.1080/00397919308009860
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