Metabolites of the Marine Sponge Dendrilla sp.

Article abstract of DOI:10.1021/jo00191a030

The sponge Dendrilla sp. was collected from a marine lake in Palau, Western Caroline Islands.Dendrilla sp. contained the known diterpenes dehydroambliol A (1) and norrisolide (2), together with the novel metabolites 1-bromo-8-ketoambliol A acetate (3), dendrillolide A (4), dendrillolide B (5), and dendrillolide C (6).The structures of the new metabolites were determined by interpretation of spectral data, application of a biosynthetic hypothesis, and chemical interconversions.