Terpenoids from the Sponge Aplysilla glacialis and Specimens of the Nudibranch Cadlina luteomarginta Found on the Sponge

Article abstract of DOI:10.1021/jo00001a010

Four new rearranged and/or degraded "spongian" terpenoids and one new "marginatane" diterpenoid have been isolated from the marine sponge Aplysilla glacialis.The structure of cadlinolide A (3) was solved by X-ray diffraction analysis, and the structures of cadlinolide B (4), aplysillolide A (5), aplysillolide B (6), and marginatone (7) were determined by extensive spectroscopic analysis and chemical interconversions.Glaciolide (2), cadlinolide A (3), and tetrahydroaplysulphurin-1 (8) were isolated from skin extracts of specimens of the dorid nudibranch Cadlina luteomarginata found feeding on A. glacialis.