N4-hydroxycytosine dioxolane nucleosides and their activity against hepatitis B virus

DOI: 10.1081/NCN-200067414

Source and publish data:

Nucleosides, nucleotides and nucleic acids p. 1209 - 1214 (2005)

Update date:2022-09-26

Topics:

Authors:

Du, Jinfa

Hollecker, Laurent

Shi, Junxing

Chun, Byoung-Kwon

Watanabe, Kyoichi A.

Schinazi, Raymond F.

Nachman, Tammy Y.

Lostia, Stefania

Stuyver, Lieven J.

Otto, Michael J.

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Article abstract of DOI:10.1081/NCN-200067414

Novel racemic, D- and L-β-dioxolane N⁴-hydroxycytosine nucleosides have been synthesized and evaluated for their activity against hepatitis B virus. None of the synthesized nucleosides demonstrated selective anti-HBV activity. Copyright Taylor & Francis, Inc.

Full text of DOI:10.1081/NCN-200067414

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