Directed lithiation of N-(tert-butoxycarbonyl)aminoisoxazole: Synthesis of 4-substituted aminoisoxazoles

DOI: 10.1016/0040-4039(96)00476-5

Source and publish data:

Tetrahedron Letters p. 3339 - 3342 (1996)

Update date:2022-08-05

Topics:

Authors:

Konoike, Toshiro

Kanda, Yasuhiko

Araki, Yoshitaka

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Article abstract of DOI:10.1016/0040-4039(96)00476-5

Directed lithiation of 3-(Boc-amino)isoxazole 4 and 5-(Boc-amino)isoxazole 9 is described. Dilithioisoxazoles reacted with a variety of electrophiles to give the corresponding 4-substituted isoxazoles.

Full text of DOI:10.1016/0040-4039(96)00476-5

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