Collection of Czechoslovak Chemical Communications p. 77 - 90 (2006)
Update date:2022-08-02
Topics:
Horejsi, Katerina
Pohl, Radek
Holy, Antonin
A novel series of tricyclic, etheno-bridged purine analogs was sythesized from 2-amino-6-(substituted amino)-9-methylpurines by cyclization with chloroacetaldehyde, with particular focus on the regioselectivity of the cyclization reaction and fluorescence properties. The analogs as well as the starting purines were alkylated with iodomethane, affording a new class of quaternary salts with potential biological activity. Neither significant fluorescence nor cytostatic effect was found.
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Doi:10.1007/BF03187328
(1959)Doi:10.1002/anie.200602787
(2006)Doi:10.1016/j.tetasy.2006.11.008
(2006)Doi:10.1021/acs.cgd.7b00308
(2017)Doi:10.1039/c5cc00411j
(2015)Doi:10.1021/ja01057a038
(1964)
