[(Aminomethyl)aryloxy]acetic acid esters. A new class of high-ceiling diuretics. 1. Effects of nitrogen and aromatic nuclear substitution

DOI: 10.1021/jm00378a010

Source and publish data:

Journal of Medicinal Chemistry p. 1579 - 1587 (1984)

Update date:2022-07-29

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Authors:

Lee Lee

Plattner

Ours Ours

Horrom Horrom

Smital Smital

Pernet Pernet

Bunnell Bunnell

El Masry

Dodge Dodge

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Article abstract of DOI:10.1021/jm00378a010

A series of Mannich bases and aminomethyl derivatives of ethyl [2,3-dichloro-4-(4-hydroxybenzoyl)phenoxy]acetate were synthesized and tested for saluretic and diuretic activities. The effects of nitrogen and aromatic nuclear substitution, reorientation of

Full text of DOI:10.1021/jm00378a010

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