[(Aminomethyl)aryloxy]acetic acid esters. A new class of high-ceiling diuretics. 1. Effects of nitrogen and aromatic nuclear substitution

DOI: 10.1021/jm00378a010

Source and publish data:

Journal of Medicinal Chemistry p. 1579 - 1587 (1984)

Update date:2022-07-29

Topics:

Authors:

Lee Lee

Plattner

Ours Ours

Horrom Horrom

Smital Smital

Pernet Pernet

Bunnell Bunnell

El Masry

Dodge Dodge

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jm00378a010

A series of Mannich bases and aminomethyl derivatives of ethyl [2,3-dichloro-4-(4-hydroxybenzoyl)phenoxy]acetate were synthesized and tested for saluretic and diuretic activities. The effects of nitrogen and aromatic nuclear substitution, reorientation of

Full text of DOI:10.1021/jm00378a010

Products guided by the article

Product name:Acetic acid, [2,3-dichloro-4-[4-hydroxy-3-(1-piperidinylmethyl)benzoyl]phenoxy]-, ethyl ester

Cas No:92270-64-9

R&D Labs maybe for 92270-64-9

Huangshi Meifeng Chemical Co.,ltd.

Contact:+86-714-6516706

Address:1941-4-3#,Hubin Avenue,Huangshi,Hubei,China
Xi'an Terra Biochem Co. Ltd.

Contact:0086-29-88315623

Address:S711, Innovation Bldg No.25 Gaoxin 1st Rd, Xian P.R of China 710075
Frapp's Chemical (NFTZ) Co.,Ltd

Contact:+86-576-86137892

Address:General Chamber of Commercial Building, 159 Wanchang Middle Road, Wenling, Zhejiang, China
Hangzhou Neway Chemicals Co., Ltd.

Contact:+86-571-85095566

Address:Room 803, Qinglian Bldg, No 139 Qingchun Road, Hangzhou, Zhejiang China
Liao Cheng All Win Chemicals Co.,LTD

Contact:86+0635-2991582

Address:Room 402,Unit 1,No.27 building.Zhong tong shi dai haoyuan,liaocheng city,Shan dong Province.China

Relevant to this article

Fluoro-ketopyranosyl nucleosides: Synthesis and biological evaluation of 3-fluoro-2-keto-β-d-glucopyranosyl derivatives of N⁴-benzoyl cytosine

Doi:10.1016/j.bmc.2006.10.033
(2007)
Development of a novel [¹⁸F]fluorobenzyl derivative of the AT₁ receptor antagonist Candesartan

Doi:10.1002/jlcr.3892
(2021)
The synthesis of some 4-deoxy-4-fluoro and 4,6-dideoxy-4,6-difluoro derivatives of sucrose

Doi:10.1016/0008-6215(84)85256-8
(1984)
Effect of ether versus ester tethering on Heck cyclizations

Doi:10.1016/j.tetlet.2005.08.072
(2005)
Conformation-activity relationship on novel 4-pyridylmethylthio derivatives with antiangiogenic activity

Doi:10.1016/j.bmcl.2008.03.068
(2008)
REACTION OF 5-HALOANTHRA<1,9-cd>-6-ISOXAZOLONES WITH AZIRIDINE

Doi:10.1007/BF00506955
(1984)

Article Doi