APPROACHES TO THE ISOQUINOLINE QUINONE ANTIBIOTICS. ADDITIONS OF AN AMINO ACID DERIVATIVE TO A QUINONE MONOACETAL.

Article abstract of DOI:10.1016/S0040-4039(01)91071-8

The addition of the benzylidene derivative of ethyl glycine to the enone system of a quinone monoacetal and subsequent aromatization provide a high yield preparation of intermediates for the synthesis of isoquinoline quinones.