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Synthesis and structure-activity study of protease inhibitors. I. (Guanidinophenyl)propionate and guanidinocinnamate derivatives

DOI: 10.1248/cpb.32.1854

Source and publish data:

Chemical and Pharmaceutical Bulletin p. 1854 - 1865 (1984)

Update date:2022-07-29

Topics: Synthesis   Yield   Bioassay   Derivatives   Mass spectrometry (MS)   IC50   Kinetics   binding affinity   HPLC (high-performance liquid chromatography)   NMR (nuclear magnetic resonance)   Enzyme inhibition   Purification   Structure-Activity Relationship (SAR)   Substrate   Protease inhibitors   Catalytic site   SAR optimization  

Authors:

OkutomeOkutome

KawamuraKawamura

TairaTaira

NakayamaNakayama

NunomuraNunomura

KurumiKurumi

SakuraiSakurai

AoyamaAoyama

FujiiFujii

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Article abstract of DOI:10.1248/cpb.32.1854

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Full text of DOI:10.1248/cpb.32.1854

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Products guided by the article

Product name:(3-Nitro-phenyl)-acetic acid phenyl ester

Cas No:93131-20-5

93131-20-5

R&D Labs maybe for 93131-20-5

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