Substituted 4,6-Diaminoquinolines as Inhibitors of C5a Receptor Binding

DOI: 10.1021/jm00080a008

Source and publish data:

Journal of Medicinal Chemistry p. 252 - 258 (1992)

Update date:2022-07-29

Topics:

Authors:

Lanza, Thomas J.

Durette, Philippe L.

Rollins, Thomas

Siciliano, Salvatore

Cianciarulo, Dana N.

et al. et al.

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Article abstract of DOI:10.1021/jm00080a008

The anaphylatoxin C5a is implicated in a number of inflammatory diseases.It is a highly cationic protein with 13 of 74 amino acids being either arginine or lysine.A search focusing on positively charged molecules, particularly amine-containing functionali

Full text of DOI:10.1021/jm00080a008

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