Study of Anopheles gambiae 3-hydroxykynurenine transaminase activity and inhibition by LC-MS/MS method

DOI: 10.1016/j.jpba.2019.05.025

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Journal of Pharmaceutical and Biomedical Analysis p. 154 - 161 (2019)

Update date:2022-09-26

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Authors:

Canavesi, Rossana

Miggiano, Riccardo

Stella, Martina

Galli, Ubaldina

Rossi, Franca

Rizzi, Menico

Del Grosso, Erika

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Article abstract of DOI:10.1016/j.jpba.2019.05.025

In Anopheles gambiae, the most efficient vector of the malaria parasite Plasmodium falciparum, 3-hydroxykynurenine is endowed with a toxic potential. In adult mosquitoes, the excess of 3-hydroxykynurenine is removed by a specific transaminase (3-hydroxyky

Full text of DOI:10.1016/j.jpba.2019.05.025

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