Syntheses and complement inhibitory activities of 4-(2-phenyl-1H-indol-3-yl)cyclohexane-1-carboxylic acids

DOI: 10.1021/jm00380a002

Source and publish data:

Journal of Medicinal Chemistry p. 160 - 164 (1985)

Update date:2022-08-05

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Authors:

Bailey Bailey

DeGrazia

Alexander

Powles Powles

Johnson Johnson

Patrick Patrick

Heerdt Heerdt

Fairbain

Pruden Pruden

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Article abstract of DOI:10.1021/jm00380a002

The syntheses of 4-(2-phenyl-1H-indol-3-yl)cyclohexane-1-carboxylic acids are described. These compounds express potent in vitro inhibition of the human classical complement pathway, and qualitative SAR have been determined. Several of the in vitro active

Full text of DOI:10.1021/jm00380a002

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