Propylphosphonic anhydride (T3P) mediated synthesis of 3-oxoisoindoline-1-carboxamides from 2-formylbenzoic acid, amines, and isocyanides. Preparation of isoindolinone alkaloids

DOI: 10.1016/j.tetlet.2018.08.063

Source and publish data:

Tetrahedron Letters p. 3683 - 3689 (2018)

Update date:2022-08-05

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Authors:

Varga, Valentina

Milen, Mátyás

ábrányi-Balogh, Péter

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Article abstract of DOI:10.1016/j.tetlet.2018.08.063

Propylphosphonic anhydride (T3P) was successfully applied to the synthesis of an isoindolinone library by the utilization of an Ugi four-center, three-component reaction (Ugi-4C-3CR). The use of T3P significantly shortened the required reaction time and t

Full text of DOI:10.1016/j.tetlet.2018.08.063

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